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The human visual cortex responds to gene therapy-mediated recovery of retinal function.
Ashtari M, Cyckowski LL, Monroe JF, Marshall KA, Chung DC, Auricchio A, Simonelli F, Leroy BP, Maguire AM, Shindler KS, Bennett J. Ashtari M, et al. Among authors: bennett j. J Clin Invest. 2011 Jun;121(6):2160-8. doi: 10.1172/JCI57377. Epub 2011 May 23. J Clin Invest. 2011. PMID: 21606598 Free PMC article. Clinical Trial.
AAV2 gene therapy readministration in three adults with congenital blindness.
Bennett J, Ashtari M, Wellman J, Marshall KA, Cyckowski LL, Chung DC, McCague S, Pierce EA, Chen Y, Bennicelli JL, Zhu X, Ying GS, Sun J, Wright JF, Auricchio A, Simonelli F, Shindler KS, Mingozzi F, High KA, Maguire AM. Bennett J, et al. Sci Transl Med. 2012 Feb 8;4(120):120ra15. doi: 10.1126/scitranslmed.3002865. Sci Transl Med. 2012. PMID: 22323828 Free PMC article. Clinical Trial.
Safety and durability of effect of contralateral-eye administration of AAV2 gene therapy in patients with childhood-onset blindness caused by RPE65 mutations: a follow-on phase 1 trial.
Bennett J, Wellman J, Marshall KA, McCague S, Ashtari M, DiStefano-Pappas J, Elci OU, Chung DC, Sun J, Wright JF, Cross DR, Aravand P, Cyckowski LL, Bennicelli JL, Mingozzi F, Auricchio A, Pierce EA, Ruggiero J, Leroy BP, Simonelli F, High KA, Maguire AM. Bennett J, et al. Lancet. 2016 Aug 13;388(10045):661-72. doi: 10.1016/S0140-6736(16)30371-3. Epub 2016 Jun 30. Lancet. 2016. PMID: 27375040 Free PMC article. Clinical Trial.
The Role of the Human Visual Cortex in Assessment of the Long-Term Durability of Retinal Gene Therapy in Follow-on RPE65 Clinical Trial Patients.
Ashtari M, Nikonova ES, Marshall KA, Young GJ, Aravand P, Pan W, Ying GS, Willett AE, Mahmoudian M, Maguire AM, Bennett J. Ashtari M, et al. Among authors: bennett j. Ophthalmology. 2017 Jun;124(6):873-883. doi: 10.1016/j.ophtha.2017.01.029. Epub 2017 Feb 23. Ophthalmology. 2017. PMID: 28237426 Free PMC article. Clinical Trial.
Compensatory Cross-Modal Plasticity Persists After Sight Restoration.
Mowad TG, Willett AE, Mahmoudian M, Lipin M, Heinecke A, Maguire AM, Bennett J, Ashtari M. Mowad TG, et al. Among authors: bennett j. Front Neurosci. 2020 May 12;14:291. doi: 10.3389/fnins.2020.00291. eCollection 2020. Front Neurosci. 2020. PMID: 32477041 Free PMC article.
5,525 results