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The establishment of a cytomegalovirus -specific CD8+ T-cell threshold by kinetic modeling for the prediction of post-hemopoietic stem cell transplant reactivation.
Zhang J, Cao J, Zheng R, Yu M, Lin Z, Wang C, McCluskey J, Yang J, Chen Z, Corbett AJ, Cao P, Mo W, Wang Z. Zhang J, et al. Among authors: mccluskey j. iScience. 2022 Oct 12;25(11):105340. doi: 10.1016/j.isci.2022.105340. eCollection 2022 Nov 18. iScience. 2022. PMID: 36325063 Free PMC article.
Quantitative affinity measurement of small molecule ligand binding to major histocompatibility complex class-I-related protein 1 MR1.
Wang CJH, Awad W, Liu L, Mak JYW, Veerapen N, Illing PT, Purcell AW, Eckle SBG, McCluskey J, Besra GS, Fairlie DP, Rossjohn J, Le Nours J. Wang CJH, et al. Among authors: mccluskey j. J Biol Chem. 2022 Dec;298(12):102714. doi: 10.1016/j.jbc.2022.102714. Epub 2022 Nov 17. J Biol Chem. 2022. PMID: 36403855 Free PMC article.
RIPK3 controls MAIT cell accumulation during development but not during infection.
Patton T, Zhao Z, Lim XY, Eddy E, Wang H, Nelson AG, Ennis B, Eckle SBG, Souter MNT, Pediongco TJ, Koay HF, Zhang JG, Djajawi TM, Louis C, Lalaoui N, Jacquelot N, Lew AM, Pellicci DG, McCluskey J, Zhan Y, Chen Z, Lawlor KE, Corbett AJ. Patton T, et al. Among authors: mccluskey j. Cell Death Dis. 2023 Feb 11;14(2):111. doi: 10.1038/s41419-023-05619-0. Cell Death Dis. 2023. PMID: 36774342 Free PMC article.
Synthetic 5-amino-6-D-ribitylaminouracil paired with inflammatory stimuli facilitates MAIT cell expansion in vivo.
Nelson AG, Wang H, Dewar PM, Eddy EM, Li S, Lim XY, Patton T, Zhou Y, Pediongco TJ, Meehan LJ, Meehan BS, Mak JYW, Fairlie DP, Stent AW, Kjer-Nielsen L, McCluskey J, Eckle SBG, Corbett AJ, Souter MNT, Chen Z. Nelson AG, et al. Among authors: mccluskey j. Front Immunol. 2023 Aug 31;14:1109759. doi: 10.3389/fimmu.2023.1109759. eCollection 2023. Front Immunol. 2023. PMID: 37720229 Free PMC article.
MAIT cell-MR1 reactivity is highly conserved across multiple divergent species.
Edmans MD, Connelley TK, Morgan S, Pediongco TJ, Jayaraman S, Juno JA, Meehan BS, Dewar PM, Maze EA, Roos EO, Paudyal B, Mak JY, Liu L, Fairlie DP, Wang H, Corbett AJ, McCluskey J, Benedictus L, Tchilian E, Klenerman P, Eckle SB. Edmans MD, et al. Among authors: mccluskey j. J Biol Chem. 2024 May 3:107338. doi: 10.1016/j.jbc.2024.107338. Online ahead of print. J Biol Chem. 2024. PMID: 38705391 Free article.
The allopurinol metabolite, oxypurinol, drives oligoclonal expansions of drug-reactive T cells in resolved hypersensitivity cases and drug-naïve healthy donors.
Mifsud NA, Illing PT, Ho R, Tuomisto JE, Fettke H, Mullan KA, McCluskey J, Rossjohn J, Vivian J, Reantragoon R, Purcell AW. Mifsud NA, et al. Among authors: mccluskey j. Allergy. 2023 Nov;78(11):2980-2993. doi: 10.1111/all.15814. Epub 2023 Jul 14. Allergy. 2023. PMID: 37452515 Free PMC article.
Bempedoic Acid and Cardiovascular Outcomes in Statin-Intolerant Patients.
Nissen SE, Lincoff AM, Brennan D, Ray KK, Mason D, Kastelein JJP, Thompson PD, Libby P, Cho L, Plutzky J, Bays HE, Moriarty PM, Menon V, Grobbee DE, Louie MJ, Chen CF, Li N, Bloedon L, Robinson P, Horner M, Sasiela WJ, McCluskey J, Davey D, Fajardo-Campos P, Petrovic P, Fedacko J, Zmuda W, Lukyanov Y, Nicholls SJ; CLEAR Outcomes Investigators. Nissen SE, et al. Among authors: mccluskey j. N Engl J Med. 2023 Apr 13;388(15):1353-1364. doi: 10.1056/NEJMoa2215024. Epub 2023 Mar 4. N Engl J Med. 2023. PMID: 36876740 Clinical Trial.
452 results